Activated Dimethicone + Magnesium Hydroxide + Aluminum Hydroxide

Activated Dimethicone + Magnesium Hydroxide + Aluminum Hydroxide Suspension belongs to the Suspensions category within the Antacids and Gastroenterology therapeutic segments — one of the highest-prescription and OTC categories in Indian pharmaceutical practice.

The clinical logic of this three-molecule combination is comprehensive:

• Magnesium Hydroxide 250 mg — a fast-acting antacid that neutralizes stomach acid quickly, providing immediate relief from burning sensations
• Dried Aluminum Hydroxide 250 mg — a slow-acting antacid that provides sustained acid neutralization and helps protect the stomach lining
• Activated Dimethicone 50 mg — an anti-flatulent that breaks down gas bubbles in the stomach and intestines, relieving bloating and discomfort

For pharmaceutical marketing companies, this product is a high-volume SKU with consistent year-round demand. Saar Biotech manufactures it from our manufacturing facility in Baddi with validated three-active suspension quality control and complete 170ml and 200ml packaging options.

At Saar Biotech, we manufacture this antacid suspension using a controlled oral suspension manufacturing process that ensures dose uniformity, palatability, and packaging reliability for the highly competitive antacid segment.

• Three-API Suspension Uniformity: Each of the three active ingredients must be uniformly distributed in the suspension vehicle. Our high-shear mixing and validated fill procedures ensure this dose-to-dose consistency.

• Taste Masking: Antacid suspensions must taste acceptable to patients who already feel unwell. We develop mint and mixed fruit-flavoured suspension bases that mask the chalky taste of the antacid components.

• pH and Stability Management: All three actives must remain chemically stable for 24 months under tropical storage conditions. Our formulation team selects preservatives, pH buffers, and suspending agents that protect all actives from chemical degradation.

• 170ml and 200ml Pack Coverage: From dark amber bottles to measuring caps and company-logo printed caps — Saar Biotech’s packaging options help antacid brands stand out at pharmacy level.

Activated Dimethicone + Magnesium Hydroxide + Aluminum Hydroxide Suspension is manufactured and supplied by Saar Biotech for the following established clinical indications:

• Dyspepsia (Indigestion): The combination provides relief from upper abdominal discomfort, bloating, and fullness after meals.

• Heartburn & Acid Reflux: Fast-acting and sustained antacid action neutralizes excess stomach acid, relieving the burning sensation associated with acid reflux.

• Flatulence & Gas: Activated Dimethicone breaks down gas bubbles in the gastrointestinal tract, providing relief from bloating and discomfort.

• Acidity & Hyperacidity: The balanced combination of antacids provides both immediate and sustained relief from acid-related symptoms.

Three-Component Clinical Mechanism

Magnesium Hydroxide is a fast-acting antacid that reacts with hydrochloric acid in the stomach to form magnesium chloride and water, neutralizing excess acid and providing rapid relief from burning sensations.

Dried Aluminum Hydroxide is a slow-acting antacid that provides sustained acid neutralization. It also forms a protective coating on the gastric mucosa, helping to protect the stomach lining from acid irritation.

Activated Dimethicone is an anti-foaming agent that reduces the surface tension of gas bubbles in the gastrointestinal tract, facilitating their expulsion and providing relief from bloating and flatulence.

Manufacturing Integrity

• Three-API Suspension Uniformity: Each active must be uniformly distributed. Our formulation team selects suspending agents that maintain uniform dispersion of all three actives.

• pH and Stability Management: The suspension vehicle must remain chemically stable for 24 months under tropical storage conditions.

• Rapid Onset of Action: Magnesium Hydroxide provides immediate acid neutralization, creating a clear clinical outcome that patients notice quickly.

• Sustained Relief: Aluminum Hydroxide provides prolonged acid neutralization, reducing the need for frequent dosing.

• Consistent Year-Round Demand: Antacids are among the highest-frequency repurchase pharmaceutical products in the Indian market.

• 170ml and 200ml Pack Logic: The 170ml format is ideal for standard treatment courses, while the 200ml format offers better value for chronic users.

Saar Biotech provides Third-Party Manufacturing and Contract Manufacturing for this antacid suspension from our dedicated oral suspension manufacturing facility in Baddi, Himachal Pradesh.

• Facility: Oral liquid and suspension manufacturing area with controlled processing, automated bottle filling, capping, labelling, and carton packing lines suited for 170ml and 200ml presentations.
• Capacity: Scalable from brand-entry launches to large commercial batches; 64×170ml, 64×200ml distributor dispatch configurations available.
• Quality Lab: In-house GLP-certified lab with validated assay for all three actives, plus pH, viscosity, suspension uniformity, MLT, and fill volume checks.
• Turnaround: New orders — 30 to 45 working days. Repeat orders — 20 to 25 working days.
• Packaging: 170ml and 200ml PET or dark amber bottles; sticker label, metallic label, measuring cup, printed cap, with-carton or without-carton supply.
• MOQ: Starting at 5,000–10,000 units per SKU.

1. Warehouse Conditions: Store below 30°C in a cool, dry environment. Do not freeze.
2. Shake Well Before Every Dose: This is the single most important user instruction for a suspension product.
3. Measuring Cup Use: A calibrated measuring cup must accompany the bottle.
4. Light Protection: Dark amber bottles and outer cartons protect the suspension from light-induced degradation.

Every commercial batch is quarantined until it passes a comprehensive analytical release protocol:

• Three-API Assay: Titrimetric confirmation of Magnesium Hydroxide and Aluminum Hydroxide, plus Activated Dimethicone content verification.
• Suspension Uniformity & Re-Dispersibility: Sediment behaviour and post-shaking uniformity are evaluated.
• pH & Viscosity Testing: The suspension vehicle’s pH and flow characteristics are monitored.
• Microbial Limit Testing (MLT): IP-compliant microbiological testing.
• Certificate of Analysis (COA): Issued with every B2B batch.

• Constipation Risk (Aluminum Hydroxide): May cause constipation, particularly with prolonged use.
• Bowel Hypomotility (Magnesium): Large doses may cause hypomotility of the bowel.
• Renal Precautions: In patients with renal impairment, plasma levels of both aluminum and magnesium may increase.
• Phosphate Depletion: Long-term use in patients with low-phosphorous diets may lead to phosphate depletion.
• Contraindications: Hypersensitivity to any constituent.

For third-party manufacturing enquiries, private-label contracts, or to request pricing and packaging options for Activated Dimethicone + Magnesium Hydroxide + Aluminum Hydroxide Suspension, please use the B2B enquiry form below.