Ofloxacin + Tinidazole Suspension

Ofloxacin + Tinidazole Suspension belongs to the Suspensions category within the Antibiotics, Gastroenterology, and Anti-Infectives therapeutic segments. This combination addresses both bacterial and protozoal causes of gastrointestinal infections.

• Ofloxacin 50mg/100mg — fluoroquinolone antibiotic effective against Gram-negative and Gram-positive bacteria
• Tinidazole 50mg/100mg — nitroimidazole effective against anaerobic bacteria and protozoa

For pharmaceutical marketing companies, this is a high-prescription anti-diarrhoeal product with consistent demand, particularly during monsoon and gastrointestinal illness seasons. Saar Biotech manufactures it from our manufacturing facility in Baddi with validated two-API suspension quality control.

At Saar Biotech, we manufacture Ofloxacin + Tinidazole Suspension using a controlled oral suspension manufacturing process that ensures dose uniformity, palatability, and packaging reliability.

• Two-API Suspension Uniformity: Both Ofloxacin and Tinidazole must be uniformly distributed to ensure consistent dosing. Our high-shear mixing and validated fill procedures ensure every 5ml dose delivers the full label claim.
• Taste Masking: Both APIs have bitter profiles requiring expert taste-masking. We develop mango and mixed fruit-flavoured suspension bases that effectively mask bitterness.
• pH and Stability Management: Both actives remain chemically stable for 24 months under tropical storage conditions.
• 60ml Pack Coverage: From dark amber bottles to drip-off embossed cartons and company-logo printed caps — our packaging options help anti-diarrhoeal brands stand out.

Ofloxacin + Tinidazole Suspension is manufactured and supplied by Saar Biotech for the following established clinical indications:

• Acute Diarrhoea: Treatment of infectious diarrhoea caused by susceptible organisms
• Dysentery: Management of bloody diarrhoea with bacterial/protozoal aetiology
• Amoebiasis: Treatment of Entamoeba histolytica infection
• Giardiasis: Treatment of Giardia lamblia infection
• Bacterial Gastroenteritis: Management of bacterial gastrointestinal infections

Schedule H — Requires valid medical prescription. Complete full course of therapy.

Two-Component Clinical Mechanism

Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, preventing bacterial DNA replication and transcription. It is effective against a wide range of Gram-negative and Gram-positive bacteria.

Tinidazole enters microbial cells and is reduced to toxic free radicals that damage microbial DNA, causing cell death. It is effective against anaerobic bacteria and protozoa.

Manufacturing Integrity

• Two-API Suspension Uniformity: Both actives must be uniformly distributed. Our suspending agent system ensures consistent dispersion.
• pH and Stability Management: The suspension vehicle is pH-buffered to maintain both actives’ chemical stability for 24 months.
• Taste Masking: Our flavour systems are engineered to mask the bitter profiles of both APIs.

• Rapid Absorption: Ofloxacin and Tinidazole are well absorbed from the GI tract, with Tmax typically achieved within 1–3 hours.
• Broad Prescriber Base: Used across gastroenterology, paediatrics, and general medicine — wide prescriber reach.
• Seasonal Demand: Consistent demand during monsoon and gastrointestinal illness seasons.
• 60ml Pack Logic: The 60ml format provides a convenient supply for 3–5 day treatment courses.

Saar Biotech provides Third-Party Manufacturing and Contract Manufacturing for Ofloxacin + Tinidazole Suspension from our dedicated oral suspension manufacturing facility in Baddi, Himachal Pradesh.

• Facility: Oral suspension manufacturing area with controlled processing, automated bottle filling, capping, labelling, and carton packing lines.
• Capacity: Scalable from brand-entry launches to large commercial batches; 160×60ml distributor dispatch configurations available.
• Quality Lab: In-house GLP-certified lab with validated HPLC assay for both actives, plus pH, viscosity, MLT, and fill volume checks.
• Turnaround: New orders — 30 to 45 working days. Repeat orders — 20 to 25 working days.
• Packaging: 60ml PET or dark amber bottles; sticker label, metallic label, measuring cup, printed cap, with/without carton.
• MOQ: Starting at 5,000–10,000 units per SKU.

1. Warehouse Conditions: Store below 30°C in a cool, dry environment. Do not freeze.
2. Shake Well Before Every Dose: Critical for uniform API distribution.
3. Measuring Cup Use: A calibrated measuring cup ensures accurate dosing.
4. Light Protection: Dark amber bottles and outer cartons protect from light-induced degradation.

Every commercial batch is quarantined until it passes a comprehensive analytical release protocol:

• Two-API HPLC Assay: Simultaneous quantification of Ofloxacin and Tinidazole against IP specifications.
• Suspension Uniformity & Re-Dispersibility: Sediment behaviour and post-shaking uniformity are evaluated.
• pH & Viscosity Testing: The suspension’s pH and flow characteristics are monitored.
• Microbial Limit Testing (MLT): IP-compliant microbiological testing.
• Certificate of Analysis (COA): Issued with every B2B batch.

• Arthropathy Risk (Ofloxacin): Ofloxacin is generally not recommended for children under 18 years except for specific indications.
• Neurological Effects (Tinidazole): May cause peripheral neuropathy with prolonged use.
• Contraindications: Hypersensitivity to fluoroquinolones or nitroimidazoles; blood dyscrasias; first trimester of pregnancy.
• Drug Interactions: Avoid alcohol during and for 3 days after Tinidazole therapy.

For third-party manufacturing enquiries, private-label contracts, or to request pricing and packaging options for Ofloxacin + Tinidazole Suspension, please use the B2B enquiry form below.