Tricholine Citrate Syrup

Tricholine Citrate Syrup belongs to the Syrups category within the Hepatology and Gastroenterology therapeutic segments. This formulation combines two complementary agents — Tricholine Citrate for hepatic support and Sorbitol as an osmotic laxative and syrup base.

Tricholine Citrate contains three molecules of choline, which plays a critical role in fat metabolism and liver function. It helps convert fat into phospholipids like lecithin, essential for biomembrane structure and function. Lecithin is also a major component of HDL (good cholesterol) and helps mobilise cholesterol from cell membranes. Sorbitol acts as both a syrup base and an osmotic laxative, drawing water into the intestinal lumen to relieve constipation. Saar Biotech manufactures this formulation from our manufacturing facility in Baddi.

At Saar Biotech, we manufacture Tricholine Citrate Syrup using a controlled oral syrup manufacturing process that ensures dose uniformity, palatability, and packaging reliability.

• API Stability Management: Tricholine Citrate is maintained in a stable formulation with appropriate pH buffering to preserve potency throughout the 24-month shelf life.
• Taste Masking: The syrup base effectively masks the characteristic taste of Tricholine Citrate while delivering a pleasant, patient-acceptable experience.
• Sorbitol Base Integration: Sorbitol serves dual purpose as both therapeutic agent and syrup base, providing consistent viscosity and palatability.
• 200ml Pack Format: From dark amber bottles to drip-off embossed cartons and company-logo printed caps — our packaging options help liver-care brands stand out at pharmacy level.

Tricholine Citrate Syrup is manufactured and supplied by Saar Biotech for the following established clinical indications:

• Constipation Management: Sorbitol’s osmotic action relieves constipation in adults and children
• Appetite Enhancement: Supports healthy appetite and digestion
• Liver Function Support: Helps prevent fatty liver diseases and hepatotoxicity
• Intestinal Peristalsis: Normalises intestinal motility
• Cholesterol Management: Supports healthy cholesterol levels through phospholipid metabolism

Use in children only under paediatrician prescription. Pregnant women should consult their physician before use.

Clinical Mechanism of Action

Tricholine Citrate contains three molecules of choline. Choline plays a key role in fat breakdown and is useful in treating fatty infiltration and improper liver function due to long-term damage. It converts fat into phospholipids like lecithin, which is essential for biomembrane structure and function. Lecithin is also a major component of HDL (good cholesterol) and helps mobilise cholesterol from cell membranes. In patients with fatty liver, increased phospholipid turnover has been observed following choline administration.

Sorbitol is hydrolysed in the colon to short-chain fatty acids, which stimulate colonic propulsive motility by drawing water into the lumen due to its osmotic action, providing effective constipation relief.

Manufacturing Integrity

• pH Stability: The syrup base is pH-buffered to maintain Tricholine Citrate’s chemical integrity.
• Uniform Distribution: Sorbitol is uniformly distributed throughout the syrup base, ensuring consistent viscosity and dosing.
• Taste Masking: The syrup’s flavour system is optimised for patient compliance.

• Dual Mechanism: Provides both hepatic support (Tricholine Citrate) and laxative action (Sorbitol) in a single formulation.
• Broad Prescriber Base: Used across hepatology, gastroenterology, and general medicine — wide prescriber reach.
• 200ml Pack Logic: The 200ml format provides a convenient supply for chronic liver and digestive health management.
• Year-Round Demand: Consistent prescription volume across liver-care and digestive health segments.

Saar Biotech provides Third-Party Manufacturing and Contract Manufacturing for Tricholine Citrate Syrup from our dedicated oral liquid manufacturing facility in Baddi, Himachal Pradesh.

• Facility: Oral liquid manufacturing area with controlled processing, automated bottle filling, capping, labelling, and carton packing lines suited for 200ml presentations.
• Capacity: Scalable from brand-entry launches to large commercial batches; 60×200ml distributor dispatch configurations available.
• Quality Lab: In-house GLP-certified lab with validated HPLC assay for Tricholine Citrate, plus pH, viscosity, MLT, and fill volume checks.
• Turnaround: New orders — 30 to 45 working days. Repeat orders — 20 to 25 working days.
• Packaging: 200ml PET or dark amber bottles; sticker label, metallic label, drip-off carton, measuring cup, printed cap, with-carton or without-carton supply.
• MOQ: Starting at 5,000–10,000 units per SKU.

1. Warehouse Conditions: Store below 30°C in a cool, dry environment. Protect from direct sunlight.
2. Light Protection: Amber bottles and outer cartons protect the syrup from photo-degradation.
3. Measuring Cup Use: A calibrated measuring cup ensures accurate 5ml dosing.
4. Dosing Instructions: Take with food and a full glass of water. Maintain a 1-hour gap before or 4-hour gap after taking other medicines.

Every commercial batch is quarantined until it passes a comprehensive analytical release protocol:

• HPLC Assay: Quantification of Tricholine Citrate 0.55g per 5ml against IP specifications.
• pH Testing: Verification that the syrup’s pH is within the stability-appropriate specification range.
• Microbial Limit Testing (MLT): IP-compliant microbiological testing confirming absence of specified pathogens.
• Certificate of Analysis (COA): Issued with every B2B batch.

• Drug Interactions: May interfere with absorption of vitamins A, D, and K. Other medicines should be taken 1 hour before or 4 hours after taking this syrup.
• Paediatric Use: Should not be given to children unless prescribed by a paediatrician.
• Pregnancy: Pregnant women should consult their physician before use.
• Side Effects: Possible nausea, gas, diarrhoea, stomach cramps, and anal irritation.
• Contraindications: Known hypersensitivity to any component.

For third-party manufacturing enquiries, private-label contracts, or to request pricing and packaging options for Tricholine Citrate Syrup, please use the B2B enquiry form below.